Bacterial and Viral Pathogens Implicated in Female Reproductive Failure Investigated on Menstrual Blood

We investigate the impact of bacterial (Chlamydia trachomatis, Ureaplasma urealyticum/parvum, Mycomplasma hominis/genitalium, Gardnerella vaginalis) and viral (HSV1/2, EBV, CMV, VZV, HHV6/HHV7, HHV8) pathogens, as a potential cause reproductive failure in women by analysis menstrual blood. analyzed DNA extracted from 48 probands selected on basis history infertility. extraction, Real-time qPCR, gel electrophoresis were applied.
 In 64.6% all tested blood samples infertile and/or pathogens detected. 41.4% we found bacterial, while 37.5% pathogens. parvum vaginalis detected 58.3% 54.2%, respectively, positive for samples. HHV7 HHV6 38.9%, 55.6%, and, 11.1% Bacterial co-infection was 22.6% patients.
 Chlamydia urealyticum, HSV1, HSV2, VZV HHV8 not samples.
 Our study offers new approach diagnostics infections upper female genital tract The opportunity to detect asymptomatic endometrium contributes reveal sterility. work clarify infectious etiology which is great importance individualized therapy.